Amazinyo akhula ngenkqubo entsonkothileyo apho izicwili ezithambileyo, ezinezicubu ezihlangeneyo, imithambo-luvo kunye nemithambo yegazi, zinxulunyaniswa neentlobo ezintathu ezahlukeneyo zethishu elukhuni ibe lilungu lomzimba elisebenzayo. Njengomzekelo ochazayo wale nkqubo, izazinzulu zihlala zisebenzisa i-incisor yegundane, ekhula ngokuqhubekayo kwaye ihlaziywe kubomi besilwanyana.

Ngaphandle kwento yokuba i-incisor yegundane ibisoloko ifundiswa kwimeko yophuhliso, imibuzo emininzi esisiseko malunga neeseli zamazinyo ezahlukeneyo, iiseli zeziqu kunye nokwahlulahlula kunye namandla eselfowuni kusafuneka kuphendulwe.

Besebenzisa indlela yokulandelelana kweeseli enye ye-RNA kunye nokulandelwa kwemfuza, abaphandi e-Karolinska Institutet, kwiDyunivesithi yaseVienna eOstriya nakwiYunivesithi yaseHarvard e-USA ngoku sele bechongile babonakalisa zonke iiseli kumazinyo empuku nakumazinyo amancinci abantu kunye nabantu abadala. .

"Ukusuka kwi-stem cells ukuya kwiiseli zabantu abadala ezahlukaniswe ngokupheleleyo sikwazile ukucacisa iindlela zokwahlulahlula ze-odontoblast, ezithi zivelise i-dentine - izicwili ezilukhuni ezikufutshane nomgubo - kunye nee-ameloblast, ezithi zenze i-enamel," yatsho isifundo sokugqibela Umbhali u-Igor Adameyko kwiSebe lePhysical and Pharmacology, Karolinska Institutet, kunye nombhali-mbhali uKaj Fried kwiSebe le-Neuroscience, Karolinska Institutet. Sikwafumene iintlobo ezintsha zeeseli kunye neeseli emazinyweni ezinokuba nendima eziyidlalayo ekuphatheni izinyo. ”

Ezinye zezinto ezifunyanisiweyo zinokucacisa izinto ezithile ezintsonkothileyo kwinkqubo yamajoni omzimba emazinyweni, kwaye ezinye zikhanyisa ukukhanya malunga nokwenziwa koqweqwe lwawo lwamazinyo, esona sicwili silukhuni emizimbeni yethu.

“Siyathemba kwaye siyakholelwa ukuba umsebenzi wethu unokuba sisiseko seendlela ezintsha zokunyanga amazinyo ngomso. Ngokukodwa, inokukhawulezisa indawo eyanda ngokukhawuleza yamayeza okuhlaziya amazinyo, unyango lwezinto eziphilayo endaweni yezicubu ezonakeleyo okanye ezilahlekileyo. ”

Iziphumo zenziwe ukuba zifikeleleke esidlangalaleni ngohlobo olunokuphicothwa olusebenzisekayo kwiiatlasi zempuku kunye namazinyo abantu. Abaphandi bakholelwa ekubeni kufuneka babonakalise ubutyebi obuluncedo kungekuphela nje kubuchwephesha bamazinyo kodwa nakwabaphandi abanomdla kuphuhliso nakwibhayoloji evuselelayo ngokubanzi.

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Izinto ezinikezwe yiKarolinska Institutet. Qaphela: Umxholo unokuhlelwa kwisitayile kunye nobude.